CO2-dependent methicillin-resistant Staphylococcus aureus.

Escherichia coli TOP10. Plasmid analysis of the K. pneumoniae isolate and its transformant confirmed that blaKPC-2 was located on an 75 kb plasmid. No other antibiotic resistance marker was co-transferred. PCR-based replicon typing of the major plasmid incompatibility groups showed that the blaKPC-2positive plasmid belonged to the IncFIIAS incompatibility group. We believe this is the first report of a KPC-producing isolate of K. pneumoniae from Switzerland. It seems likely that the isolate was imported as a result of the transfer of a patient from Sicily. In Italy, several studies reported KPC-2or KPC-3-producing K. pneumoniae isolates, being mostly of ST258 type. There is a need for urgent action to slow down and control the worldwide and epidemic spread of enterobacterial carbapenemase producers, including countries with a low level of antibiotic resistance, such as Switzerland.